Trust your heart health with Nature Made Fish Oil 1000 mg. Every 2 softgels provide 500 mg of heart healthy EPA and DHA omega-3s. Nature Made’s Burp-Less formula Fish Oil is specially coated to help prevent a fishy odor and aftertaste. Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.
Dr. Goldberg teaches these patients to monitor their blood pressure at home in the mornings and evenings. This gives her a more complete picture before prescribing any medications. But there’s a hidden benefit, as well: Research suggests that keeping track of their own blood pressure may be incentive for patients to make healthy choices like losing weight and eating healthier. 

Blood pressure fluctuates throughout the day, so measuring it in the morning might yield a different number than, say, the afternoon. Conditions like stress and lack of sleep can also fluctuate blood pressure. Visiting your doctor might feel nerve-wracking, which can elevate your blood pressure and create a condition called white coat hypertension.

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Omega-3 fats are typically found in flaxseed oil, walnut oil and fish, with fish being by far the best source. Unfortunately, most fresh fish today contains dangerously high levels of mercury. Your best bet is to find a safe source of fish, or if this proves too difficult, supplement with a high quality krill oil, which has been found to be 48 times more potent than fish oil.
If you have been diagnosed with high blood pressure, your long-term health depends on keeping the condition under control.  The changes above can all help reduce blood pressure levels to a healthy range and potentially allow you to avoid the need for medication.  Still, this is a determination that can only be made by your physician.  Speak with your doctor about your potential treatment options and which may be best for your particular situation.
2. Take an omega-3 oil. Omega 6:3 ratio is important. A lot of us get way too much omega-6 in our diets, which is what's caused the omega-3 craze. Refined vegetable oil is one of the main culprits, and found in almost all processed foods, and even some orange juices. Because we have way too much omega-6 in our systems, we need to compensate by taking some form of omega-3 oil. Decreasing your intake of processed foods will have a similar effect.

One 12 ounce bottle of soda contains about 40 grams of fructose, one of the leading high blood pressure risk factors in North America. Consuming 74 or more grams of fructose per day increases your risk of high blood pressure by 77 percent. For people who are accustomed to drinking a can or two of soda daily, cutting the pop can have a dramatic effect on blood pressure, even eliminating the problem altogether.
Napping may do your heart some good. Adults with high blood pressure who took hour-long naps every day saw their systolic blood pressure drop an average of 5% over the course of the day in a 2015 study, compared to those who didn’t rest. Those who napped also had to take fewer blood pressure medications than those who didn’t, and seemed to have less damage to their arteries and their heart. The study was only able to show a correlation between napping and blood pressure reduction, but the authors say that the results do suggest a benefit to afternoon siestas. 
3. Eat a healthy diet. Food is another powerful medicine. Whether you need to lose weight or not, eating well can improve your blood pressure. That means eating fruits and vegetables, whole grains, healthy oils (such as olive and canola), foods rich in omega-3 fatty acids (salmon, tuna, walnuts and flaxseed, for example) and two or three servings daily of low-fat or nonfat dairy products. It also means avoiding saturated and trans fats.
There are more worrisome facts about medications, notes Dr. Fruge.  Drug treatment frequently has annoying and sometimes dangerous side effects, and never cures the disease.  All too often, blood pressure problems grow progressively worse despite the use of medications.  That’s deeply troubling because hypertension is a major risk factor for heart attacks, strokes, heart failure, cardiac arrhythmia, and premature death.
Kidneys depend on healthy blood vessels to function properly, proper kidney function is crucial to filtering excess fluid and waste from your blood. High blood pressure can damage your kidneys leading to kidney disease (nephropathy). High blood pressure is the most common cause of kidney failure. Kidney failure leads to either dialysis or a kidney transplant, because your own body can no longer filter the waste and excess fluid from your body. 
For example, eating a healthy diet rich in fruit, vegetables, whole grains, and healthy fats can limit dense low-density lipoprotein (LDL) deposits along the artery that contribute to high blood pressure. Limiting intake of processed foods can lower sodium intake and total cholesterol. This, in addition to exercise, can also help lead to weight loss. Research indicates that losing as little as nine pounds can have substantial impacts on blood pressure.
One notable recommendation within the new guidelines is the focus on lifestyle changes first, and medication only if necessary. Like all meds, blood pressure medications come with their side effects, so it’s always worth it to work on diet, exercise and stress management first. Even if an individual receives only partial benefits from lifestyle changes, it may still mean reduced medication usage, or one with fewer side effects if necessary. Here are a few lifestyle changes that you start today to reduce your blood pressure naturally.
If you happen to love any of the above alternative approaches, or are doing it as part of your healthy lifestyle, you can continue to do so. Remember they complement, and not necessarily replace traditional approaches and medications that your doctor suggests. You might see only a modest reduction in your blood pressure, but you know what...it is probably not going to hurt either!
How do you check your own blood pressure? It is common to have your blood pressure checked at the doctor's office, but there are many cases where it is important to monitor it at home. It is easy to check blood pressure with an automated machine, but it can also be done manually at home. Learn how to check your own blood pressure and what the results mean. Read now
One notable recommendation within the new guidelines is the focus on lifestyle changes first, and medication only if necessary. Like all meds, blood pressure medications come with their side effects, so it’s always worth it to work on diet, exercise and stress management first. Even if an individual receives only partial benefits from lifestyle changes, it may still mean reduced medication usage, or one with fewer side effects if necessary. Here are a few lifestyle changes that you start today to reduce your blood pressure naturally.
We asked clinicians from Beth Israel Deaconess Medical Center’s CardioVascular Institute how they advise their patients to keep blood pressure under control. While medication is the right solution for some people, the good news is that lifestyle changes can help reduce — and in some cases replace — the amount of medication needed. It’s a good place to start.

An aside: We don't much like taking medications, either. But if you end up needing blood pressure medicine to achieve a healthy blood pressure, don't be discouraged. The medicines are effective and safe, and they present only mild side effects, if any. Studies comparing older and newer blood pressure medicines found that one of the oldest and cheapest classes of drugs (the thiazide diuretics, such as hydrochlorothiazide and chlorthalidone) was as good as, or better than, the newer, more expensive ones.
For example, eating a healthy diet rich in fruit, vegetables, whole grains, and healthy fats can limit dense low-density lipoprotein (LDL) deposits along the artery that contribute to high blood pressure. Limiting intake of processed foods can lower sodium intake and total cholesterol. This, in addition to exercise, can also help lead to weight loss. Research indicates that losing as little as nine pounds can have substantial impacts on blood pressure.
Now I work with patients with high blood pressure every single day in my clinic. I’m board-certified chiropractic physician and people come into my office all the time with high blood pressure. And over the years I learned that traditional lifestyle changes do not have the answers for these patients. On top of that many hate the idea of taking drugs to manage their high blood pressure. 

What these scientists found was that while drug treatments for mild hypertension may be effective at lowering blood pressure, they were not effective in reducing overall mortality. Put more bluntly, hypertension patients in these studies died at about the same rate whether they took medication or not. These findings reaffirm an important health principle: Treating the symptoms of disease is not the same thing as causing health.


WebMD states the goal of lowering blood pressure immediately during a hypertensive emergency is to prevent further organ damage. Doctors may perform eye exams in a hypertensive emergency to monitor possible organ damage. Blood and urine samples are also taken. Symptoms of a hypertensive emergency include headache, blurred vision, seizure, increasing chest pain, increasing shortness of breath and fluid buildup in tissues.
Don’t assume that your doctor is aware of these facts. If you are diagnosed with mild, high blood pressure, you likely will be prescribed medication, instructed that it is helpful, and told that you must take it for the rest of your life. But before accepting this potentially dangerous treatment, it may be to your advantage to seek answers to the following questions: “What caused my high blood pressure?” and “Can I remove those causes and reverse this condition?”
These methods will reduce blood pressure immediately, and some, like exercise, keep blood pressure down for nearly 24 hours. However, all methods should be made part of a regular daily lifestyle for the changes to be effective. Unmanaged and untreated high blood pressure can lead to kidney and heart failure, stroke, and many other potentially fatal conditions.
It's time to heed your partner's complaints and get that snoring checked out. Loud, incessant snores are a symptom of obstructive sleep apnea (OSA), a disorder characterized by brief yet potentially life-threatening interruptions in breathing during sleep. And many sleep apnea sufferers also have high levels of aldosterone, a hormone that can boost blood pressure, according to University of Alabama researchers. In fact, it's estimated that sleep apnea affects half of people with high blood pressure.
8. Take less stress: If you want to stay healthy, take less stress. Every individual faces some kind of difficulty in their life. What matters is the attitude you have towards these difficulties. If you constantly take stress or tension, you are likely to have blood pressure problems. Being chronically stressed puts your body in constant fight-or-flight mode. This could lead to faster heart rate and constricted blood vessels. Listen to good music, do yoga, meditate. These are some effective ways to control your stress and also keep your blood pressure under control.
This is an interesting thread. I take 400 mg per day of Magnesium on the advice of my naturopath, have done so for a few years now, with some cycling on and off. I successfully manage my tendency towards hypertension through this one simple action (although constantly improving my health in other ways has its’ effects I’m sure!). I find when I cycle off it for too long I start to get muscle cramps and insomnia as well. I have observed a familial link between muscle pain and cramps in my maternal lineage, and believe there is some kind of genetic/epigenetic link to how our family utilises Mg in the body although I have no proof or idea of the mechanism of this. All I know is I’d prefer to supplement Mg moderately than take pharmaceuticals. I look forward to the day I can explain this with science (as I’m a scientist!) – would love any thoughts from Chris or the Kresser Institute experts on this 😊

If you are in this 130/80 range, reducing your blood pressure can help protect you from heart attack, stroke, kidney disease, eye disease, and even cognitive decline. The goal of the new guidelines is to encourage you to treat your high blood pressure seriously and to take action to bring it down, primarily using lifestyle interventions. "It is well documented that lifestyle changes can lower blood pressure as much as pills can, and sometimes even more," says Dr. Fisher.

A 2013 study published in “Hypertension” concluded that flaxseed lowers blood pressure in hypertensive patients. It is a great home remedy for high blood pressure. More than 100 patients diagnosed with peripheral artery disease, a condition associated with high blood pressure, were assigned to a flaxseed group or a placebo group. The former ate 30 grams of flaxseed every day for 6 months.
According to the Centers for Disease Control and Prevention (CDC), an estimated 75 million Americans have high blood pressure. Many risk factors for high blood pressure are out of your control, such as age, family history, gender, and race. But there are also factors you can control, such as exercise and diet. A diet that can help control blood pressure is rich in potassium, magnesium, and fiber and lower in sodium.
One drink counts as 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of spirits. "High levels of alcohol are clearly detrimental," says Obarzanek. "But moderate alcohol is protective of the heart. If you are going to drink, drink moderately." (And if you're trying to keep your weight in check, stick to these low-calorie alcoholic drinks recommended by registered dietitians.)

The reasons for this astonishing success are not yet entirely understood. Certainly, two of the major causes of high blood pressure are being addressed: excessive dietary salt is completely eliminated, and it is likely that some patients experience some reversal of the atherosclerosis process. However, Dr. Campbell has suggested that additional mechanisms may be partly responsible for fasting’s remarkable effects, such as the rapid reduction of a phenomenon known as “insulin resistance.”
One of the top causes for heart disease is high blood pressure. High blood pressure is one condition which might not show any symptoms for a really long time. Read here to know some effective ways to control your blood pressure.  By: DoctorNDTV  Updated: Oct 24, 2018 09:26 IST 4-Min Read 114 SHARES High blood pressure can be controlled by maintaining a healthy lifestyle
Most types of exercise: aerobic, weight training, and isometric hand-grip exercises helped patients lower blood pressure, with people doing isometric hand-grip exercises showing the most blood pressure reduction (about 10 percent). This was greater than the benefit obtained from a mild aerobic exercise like walking. However, the researchers speculated that this could be related to the lack of intensity or shorter duration of walking done by the subjects. Some older studies have indicated that intense walking over 35 minutes done regularly confers the same cardiovascular benefits. Comparing various alternative approaches, exercise has some of the strongest evidence out there for lowering high blood pressure. 

3. Quit soda. One 12-ounce can of soda contains about 40 grams of fructose, one of the leading high blood pressure risk factors in North America. Consuming 74 or more grams of fructose per day increases your risk of high blood pressure by 77 percent. For people accustomed to drinking a can or two of soda daily, cutting the pop can have a dramatic effect on blood pressure, even eliminating the problem altogether.
8. Take less stress: If you want to stay healthy, take less stress. Every individual faces some kind of difficulty in their life. What matters is the attitude you have towards these difficulties. If you constantly take stress or tension, you are likely to have blood pressure problems. Being chronically stressed puts your body in constant fight-or-flight mode. This could lead to faster heart rate and constricted blood vessels. Listen to good music, do yoga, meditate. These are some effective ways to control your stress and also keep your blood pressure under control.
Ginger, the spicy root often used in Asian cooking, could also help lower blood pressure. According to M. Jan Ghayur and A. Gilani from The Aga Khan University Medical College in Pakistan and published in the January 2005 issue of the "Journal of Cardiovascular Pharmacology," ginger can reduce blood pressure by blocking the voltage-dependent calcium channels. MedlinePlus agrees that ginger does reduce high blood pressure, but individuals who take medication for their high blood pressure should use ginger with precaution because ginger might lower it too much or cause an irregular heartbeat.
An aside: We don't much like taking medications, either. But if you end up needing blood pressure medicine to achieve a healthy blood pressure, don't be discouraged. The medicines are effective and safe, and they present only mild side effects, if any. Studies comparing older and newer blood pressure medicines found that one of the oldest and cheapest classes of drugs (the thiazide diuretics, such as hydrochlorothiazide and chlorthalidone) was as good as, or better than, the newer, more expensive ones.
Americans eat far too much dietary sodium, up to three times the recommended total amount, which is 1,500 milligrams (mg) daily for individuals with high blood pressure, says Dr. Fisher. It doesn't take much sodium to reach that 1,500-mg daily cap — just 3/4 of a teaspoon of salt. There's half of that amount of sodium in one Egg McMuffin breakfast sandwich. Weed out high-sodium foods by reading labels carefully. "It is very difficult to lower dietary sodium without reading labels, unless you prepare all of your own food," says Dr. Fisher. Beware in particular of what the American Heart Association has dubbed the "salty six," common foods where high amounts of sodium may be lurking:
Since there’s such a large variety of herbal remedies and so many different medications for blood pressure that are commonly prescribed today, this isn’t a simple question. However, there certainly exists the potential for negative herb-drug interactions and complications. My best advice is to discuss your specific herbal medications with your prescribing doctor, so that they will be aware of, and monitor closely for, any potential interactions.
Start by eating nuts. Pistachio nuts, singled out among other nuts, seem to have the strongest effect on reducing blood pressure in adults. This is according to a recent review and scientific analysis of 21 clinical trials, all carried out between 1958 and 2013. The review appears online in The American Journal of Clinical Nutrition, a publication of the American Society for Nutrition. 

Drugs.com explains diazoxide is used in emergency situations when severe high blood pressure occurs in adults and children. This medication lowers diastolic pressure in children. The drug increases cardiac output when blood pressure lowers, thereby making the heart work less. Hyperglycemia may occur as a side effect, but that condition usually occurs in patients with diabetes. Repeated injections of diazoxide may result in congestive heart failure since the medication causes sodium retention.
7. Cut down on sodium intake: Processed and packaged food needs to go out of your kitchen, if you want healthy levels of blood pressure. This is because processed food is loaded with added preservatives to increase their shelf life. Also, prepare your food with lesser salt as high intake of salt is linked to risks of high blood pressure and stroke.

One of the top causes for heart disease is high blood pressure. High blood pressure is one condition which might not show any symptoms for a really long time. Read here to know some effective ways to control your blood pressure.  By: DoctorNDTV  Updated: Oct 24, 2018 09:26 IST 4-Min Read 114 SHARES High blood pressure can be controlled by maintaining a healthy lifestyle
In fact, a review of Figure 2 indicates that the most impressive results were observed with the most serious cases. In cases of “moderate” to “severe” hypertension (blood pressures of 174/93 or greater), the average reduction at the conclusion of treatment was a remarkable 46/15! For these cases, which medical practitioners generally would insist need lifetime medical intervention, the average exit blood pressure was 128/78, using no medication whatsoever!
Since there’s such a large variety of herbal remedies and so many different medications for blood pressure that are commonly prescribed today, this isn’t a simple question. However, there certainly exists the potential for negative herb-drug interactions and complications. My best advice is to discuss your specific herbal medications with your prescribing doctor, so that they will be aware of, and monitor closely for, any potential interactions.
Over a 12-year period, 174 patients diagnosed with mild to severe high blood pressure were seen at the Center for Conservative Therapy and were placed on a medically-supervised, water-only fasting regime. The treatment procedure included an average water-only fasting period of 10.6 days, followed by a supervised refeeding period of about one week with a whole, natural foods diet. The results of the study are summarized in Figure 2.
This technique is known to surprisingly few health professionals, though it has proved valuable in the treatment of a wide variety of health problems. Recently, this powerful technique has been shown to be an extremely effective method for allowing the body to rapidly normalize high blood pressure more effectively than any other treatment reported in the scientific literature.
As much as I want, these alternative therapies do not replace traditional approaches for blood pressure control (low salt diet, medications). The best way to look at them is as strategies to complement what your doctor has already been prescribing you for your high blood pressure. This could really help if you have mild hypertension, where alternative therapies could potentially help you get off your blood pressure medications, but I highly doubt anyone with severe hypertension is getting off their Norvasc just because they started doing transcendental meditation. 
Note: The fasting and high blood pressure study described in this article was funded in part by a grant from the National Health Association. It was conducted at the Center for Conservative Therapy in Penngrove, California. The results appeared in the article, “Medically Supervised Water-Only Fasting in the Treatment of Hypertension,” published in June 2001 in the Journal of Manipulative and Physiological Therapeutics.

If you have been diagnosed with high blood pressure, your long-term health depends on keeping the condition under control.  The changes above can all help reduce blood pressure levels to a healthy range and potentially allow you to avoid the need for medication.  Still, this is a determination that can only be made by your physician.  Speak with your doctor about your potential treatment options and which may be best for your particular situation. 

I do all of that. I as on bp meds for 10 years, got sick in 2008, went off all pharma meds, got lots of help from alternative medicine, was off all pharma meds for 9 years and completely and totally changed my diet and lifestyle, then in Oct 2016 my bp started to climb again and, after I had hernia surgery in Nov 2016, my bp went sky-high and won’t come back down no matter what alternative thing I do and won’t stay down unless I am taking bp pills. My primary doctor and cardiologist are trying to say I have essential hypertension–when I was off all bp and pharma meds for 9 years and had no issues with my bp. Nope. Not buying it. Baffled to the high heavens why this time, I can’t seem to get back off bp meds. Working on lots of different things, but haven’t found that magic “aha” item that is causing this yet. Started NP Thyroid and low-dose Naltrexone for hypo/Hashi and all-over body pain/autoimmune and am hoping once they help stabilize my body processes that maybe they will also impact the hbp. Also naturally taking care of female hormones that are off (postmenopausal at age 50).

According to the Centers for Disease Control and Prevention (CDC), an estimated 75 million Americans have high blood pressure. Many risk factors for high blood pressure are out of your control, such as age, family history, gender, and race. But there are also factors you can control, such as exercise and diet. A diet that can help control blood pressure is rich in potassium, magnesium, and fiber and lower in sodium.
Cinnamon is another tasty seasoning that requires little effort to include in your daily diet, and it may bring your blood pressure numbers down. One study done in rodents suggested that cinnamon extract lowered both sudden-onset and prolonged high blood pressure. However, the extract was given intravenously. It’s unclear if cinnamon consumed orally is also effective.
First, keep in mind that drugs have limited success. Most studies on diuretics and other blood pressure-lowering drugs suggest they lower the risk of cardiovascular events among those with blood pressure between 140/90 and 159/99 by 15 to 20%.3 The problem is, with this range of blood pressure, the risk of cardiovascular-related deaths has increased by 300 to 400% compared to people with normal blood pressure.
Ask your doctor if low-fat or nonfat milk is better than whole milk for you. Whole milk can lower blood pressure better than low-fat or nonfat milk, but there may also be risks. Whole milk contains Palmitic acid, which, according to some studies, can block internal signals responsible for relaxing blood vessels. As a result, your blood vessels stay constricted and your blood pressure remains high.[7]

Consuming garlic is one of the fastest ways to reduce your blood pressure. According to Gloria Benavides, Ph.D., and David Kraus, Ph.D., of Alabama-based UAB Health System, eating garlic not only lowers your blood pressure but also can protect you against cardiovascular disease. They state that the compounds from garlic interact with your red blood cells, which allow your blood vessels to relax and your pressure to naturally lower. In a study published in the July-August 1993 issue of the journal "Pharmacotherapy," F. McMahon and colleagues proved that garlic reduces blood pressure. In this study, participants who had severe hypertension were given a garlic solution of 2,400mg of garlic containing 1.3 percent allicin, an organosulfur compound found in garlic that has anti-fungal and antibacterial properties. In less than five hours, the participants' sitting blood pressure fell 7/16 mm Hg and within five to 14 hours, all their diastolic pressures dropped significantly.
A lack of vitamin D is common in developed countries and can cause a range of health problems. But this simple and inexpensive supplement may reduce the risk of cardiovascular disease. Taking around 4000IU of a high-quality D3 supplement daily can also support bone health, lower blood pressure, boost your mood and reduce fatigue – and these are just a few of its many health benefits.
In a 2014 review of previous studies, people who consumed probiotics—healthy bacteria found in yogurt and other fermented foods—saw their systolic blood pressure reduced an average of 3.6 points, and their diastolic reduced 2.4 points, compared to those who didn’t. Those with blood pressure higher than 130/85 experienced the greatest reductions, along with those who took probiotic supplements or ate probiotic foods for longer than two months. (Any blood pressure over 120/80 mm Hg is considered elevated.) Experts say any effect probiotics have on blood pressure is likely modest, but that they may play a role in an overall heart-healthy lifestyle.
Magnesium. High magnesium intake is associated with lower blood pressure and may have a synergistic effect with potassium. Increasing both nutrients while moderately reducing sodium can lower blood pressure to the same extent as a single medication (17). Magnesium stimulates vasodilators and can inhibit free radical formation in blood vessels (18). Nuts, seeds, spinach, beet greens, and chocolate are good whole food sources.
It can also be put into common foods and soups (a few tablespoons of the liquid will do), to hide the flavor in regular meals. Apple cider vinegar is often drunk as a healthy morning tonic and combined with lemon juice, warm water, and a dash of organic honey, can be a rather tasty beverage that not only helps to lower high blood pressure but gives your body a metabolic boost to start the day with as well.

One of the easiest ways to manage your blood pressure is simply making healthy life choices such as eating low-sodium diet, committing to a regular exercise routine, and avoiding (excessive) alcohol. Smoking is one of the worst things that you can do to your cardiovascular system, and it’s important that you take steps to quit as soon as possible to avoid hypertension, even if you don’t yet suffer from it yet. 


Today's episode of the OPP we feature guest Joe Scola, who is the founder of Wise Ape Tea. They specialize in Adaptogenic teas, which regulate stress for your body. We get into some HEAVY Tea Topics like the weirdest blend of tea, the historic origins of tea, and discuss how adding in CBDs affects tea. Wise Ape also partners with many organizations, and for each tea sale they donate a chunk of the proceeds to these organizations which is awesome! Each tea is partnered with a specific charitable organization so go out there, buy your favorite tea, and contribute to a great cause! Two birds with one stone!

How low should you go? Aim to keep your sodium intake below 1,500 mg for healthy blood pressure, recommends the American Heart Association. That’s about half of what most Americans consume per day. Going easy on the saltshaker can help, but you’ll make a bigger impact by watching the sodium count in packaged or processed foods, Obarzanek says. (Pay extra attention to bread and rolls, pizza, soup, cold cuts, poultry, and sandwiches, which tend to pack the most salt.) Then try these other simple ways to slash your salt intake.
Eat dark chocolate. Dark chocolate and cocoa powder are both full of heart-healthy plant compounds called flavonoids. Flavonoids are good for you because they cause your blood vessels to dilate, which can help lower blood pressure. Just make sure your chocolate doesn’t have too much sugar. Choose chocolate that is at least 70 percent dark for best results. You can buy individually wrapped chocolate pieces that are the perfect size. Eat one or two a day and enjoy the delicious heart-protective effects.
Studying men with hypertension who came to Pritikin, scientists at UCLA found that within three weeks, the men had significantly healthier levels of blood pressure. In fact, those who arrived at Pritikin taking hypertension drugs left Pritikin two to three weeks later no longer needing their medications, or with their dosages significantly reduced.1
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